Molluscum contagiosum

  • Epidemiologia
    • Doentes com dermatite atópica - menos resistência da pele, autoinoculação de coçar
    • Imunossupressão - SIDA
  • Transmissão
    • Molluscum contagiosum is considered a sexually transmitted infection (STI) because it can be spread through sexual contact.
    • However, it can also be spread through non-sexual skin-to-skin contact, such as sharing towels or touching infected skin
  • Apresentação clínica
    • Hemispherical translycent pink papules
    • 1-5mm in diameter
    • Arranged in clusters
    • Umbilicação central
    • Crown vessels
  • DDx
    • in HIV patients
      • Criptococose cutânea é muito parecido - suspeitar se doente imunodeprimido (especialmente se CD4<250)
      • Penicilliosis
      • Histoplasmosis
  • Histology
    • Very typical
    • Acanthotic epidermis invaginated into peri-lobular forms
    • Infected cells arranged like fruit in a bowl, containing very large intracytoplasmic inclusion body, hyaline, eosinophilic then basophilic molluscum contagiosum corpuscles
  • Tratamento
    • Curetagem
    • Crioterapia
    • Mollusk
    • Molutrex
    • Aldara 3x/sem 12-16 semanas
    • 5% salicylic acid
    • 2,5-10% KOH
    • Tazarotene
    • Liquefied phenol
    • Cantharidin
    • Tretinoin
    • Podophyllotoxin