Pseudoporphyria | bullous dermatosis of dialysis

  • Etiology
    • Chronic renal disease
      • Also reffered as bullous dermatosis of dialysis
    • Hemodialysis
      • Inefectiveness of hemodialysis to remove porphyrias
    • Drugs
      • Most likely culprit: naproxen
      • Propionic acid derivative NSAIDs: Naproxen, Ketoprofen
      • Furosemide, thiazides, tetracyclines, ciprofloxacin, isotretinoin → effect on liver metabolism
          • notion image
    • Tanning beds
  • Apresentação clínica
    • Clinical features of porphyria cutanea tarda without abnormality in porphyrin metabolism
      • Also show Blisters, scars, millia → clinically and histological identical to PCT
      • No abnormalities in porphyrin metabolism are detected
  • Tratamento
    • Discontinution of suspected drug and sun protection