Episodic angioedema with eosinophilia (Gleich syndrome)

Etiology
  • Activation of T Lymphocutes by an unknown stimulus
  • Elevated IL5
 
Clinical presentation
  • Episodic manifestions combining febrile edema, weight gain and eosinophilia
  • Angioedema
  • Urticaria
  • Significant weight gain
 
Exames complementares
  • Eosinophilia
  • May be associated with polyclonal IgM
 
Treatment
  • Corticosteroids